SCOPe 2.08: Domain d4bggc_: 4bgg C:

Lineage for d4bggc_ (4bgg C:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d4bggc_: 4bgg C: [219481]
   automated match to d3tzma_
   complexed with 844, edo, flc

Details for d4bggc_

PDB Entry: 4bgg, 2.56 Å

PDB Description: Crystal structure of the ACVR1 kinase in complex with LDN-213844

PDB Compounds: (C:) Activin receptor type-1

SCOPe Domain Sequences for d4bggc_:

Sequence, based on SEQRES records:

>d4bggc_ d.144.1.7 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
varditllecvgkgrygevwrgswqgenvavkifssrdekswfretelyntvmlrhenil
gfiasdmtsrhsstqlwlithyhemgslydylqlttldtvsclrivlsiasglahlhiei
fgtqgkpaiahrdlksknilvkkngqcciadlglavmhsqstnqldvgnnprvgtkryma
pevldetiqvdcfdsykrvdiwafglvlwevarrmvsngivedykppfydvvpndpsfed
mrkvvcvdqqrpnipnrwfsdptltslaklmkecwyqnpsarltalrikktltk

Sequence, based on observed residues (ATOM records):

>d4bggc_ d.144.1.7 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
varditllecvgkgrygevwrgswqgenvavkifssrdekswfretelyntvmlrhenil
gfiasdmtsrhsstqlwlithyhemgslydylqlttldtvsclrivlsiasglahlhiei
gkpaiahrdlksknilvkkngqcciadlglavmhsqstnvgnnprvgtkrymapevldet
iqvdcfdsykrvdiwafglvlwevaredykppfydvvpndpsfedmrkvvcvdqqrpnip
nrwfsdptltslaklmkecwyqnpsarltalrikktltk

Timeline for d4bggc_:

• d4bggc_ first appeared in SCOPe 2.03
  
• d4bggc_ appears in SCOPe 2.07