SCOPe 2.06: Domain d4bggb_: 4bgg B:

Lineage for d4bggb_ (4bgg B:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (17 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (653 PDB entries)

8. Domain d4bggb_: 4bgg B: [219480]
   automated match to d3tzma_
   complexed with 844, edo, flc

Details for d4bggb_

PDB Entry: 4bgg, 2.56 Å

PDB Description: Crystal structure of the ACVR1 kinase in complex with LDN-213844

PDB Compounds: (B:) Activin receptor type-1

SCOPe Domain Sequences for d4bggb_:

Sequence, based on SEQRES records:

>d4bggb_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tvarditllecvgkgrygevwrgswqgenvavkifssrdekswfretelyntvmlrheni
lgfiasdmtsrhsstqlwlithyhemgslydylqlttldtvsclrivlsiasglahlhie
ifgtqgkpaiahrdlksknilvkkngqcciadlglavmhsqstnqldvgnnprvgtkrym
apevldetiqvdcfdsykrvdiwafglvlwevarrmvsngivedykppfydvvpndpsfe
dmrkvvcvdqqrpnipnrwfsdptltslaklmkecwyqnpsarltalrikktltki

Sequence, based on observed residues (ATOM records):

>d4bggb_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tvarditllecvgkgrygevwrgswqgenvavkifssrdekswfretelyntvmlrheni
lgfiasdmtsrhsstqlwlithyhemgslydylqlttldtvsclrivlsiasglahlhie
ifgkpaiahrdlksknilvkkngqcciadlglavmhsqstnqldvgnnprvgtkrymape
vldetiqvdcfdsykrvdiwafglvlwevarrmvsngivedykppfydvvpndpsfedmr
kvvcvdqqrpnipnrwfsdptltslaklmkecwyqnpsarltalrikktltki

Timeline for d4bggb_:

• d4bggb_ first appeared in SCOPe 2.03
  
• d4bggb_ appears in SCOPe 2.05
  
• d4bggb_ appears in SCOPe 2.07
  
• d4bggb_ appears in the current release, SCOPe 2.08