SCOPe 2.06: Domain d4bbmb1: 4bbm B:1-308

Lineage for d4bbmb1 (4bbm B:1-308)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (25 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (882 PDB entries)

8. Domain d4bbmb1: 4bbm B:1-308 [219407]
   Other proteins in same PDB: d4bbma2, d4bbmb2
   automated match to d3blra_
   complexed with cl, edo, tc0

Details for d4bbmb1

PDB Entry: 4bbm, 2 Å

PDB Description: crystal structure of the human cdkl2 kinase domain with bound tcs 2312

PDB Compounds: (B:) cyclin-dependent kinase-like 2

SCOPe Domain Sequences for d4bbmb1:

Sequence, based on SEQRES records:

>d4bbmb1 d.144.1.0 (B:1-308) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mekyenlglvgegsygmvmkcrnkdtgrivaikkflesdddkmvkkiamreikllkqlrh
enlvnllevckkkkrwylvfefvdhtilddlelfpngldyqvvqkylfqiingigfchsh
niihrdikpenilvsqsgvvklcdfgfartlaapgevyddevatrwyrapellvgdvkyg
kavdvwaigclvtemfmgeplfpgdsdidqlyhimmclgnliprhqelfnknpvfagvrl
peikereplerrypklsevvidlakkclhidpdkrpfcaellhhdffqmdgfaerfsqel
qlkvqkda

Sequence, based on observed residues (ATOM records):

>d4bbmb1 d.144.1.0 (B:1-308) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mekyenlgsygmvmkcrnkdtgrivaikkfkkiamreikllkqlrhenlvnllevcylvf
efvdhtilddlelfpngldyqvvqkylfqiingigfchshniihrdikpenilvsqsgvv
klcdfgfartlaapgevyddevatrwyrapellvgdvkygkavdvwaigclvtemfmgep
lfpgdsdidqlyhimmclgnliprhqelfnknpvfagvrlpeikereplerrypklsevv
idlakkclhidpdkrpfcaellhhdffqmdgfaerfsqelqlkvqkda

Timeline for d4bbmb1:

• d4bbmb1 first appeared in SCOPe 2.03, called d4bbmb_
  
• d4bbmb1 was called d4bbmb_ in SCOPe 2.05
  
• d4bbmb1 appears in SCOPe 2.07
  
• d4bbmb1 appears in the current release, SCOPe 2.08