Lineage for d4ajra_ (4ajr A:)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2479470Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
    consists of two intertwined (sub)domains related by pseudo dyad; duplication
    3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest
  4. 2479471Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families) (S)
    the constituent families form similar dimers
  5. 2479472Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (4 protein domains)
    the active site is between the two identical subunits
  6. 2479631Protein automated matches [190072] (19 species)
    not a true protein
  7. 2479692Species Escherichia coli [TaxId:562] [193425] (5 PDB entries)
  8. 2479696Domain d4ajra_: 4ajr A: [219005]
    automated match to d4ajca_
    complexed with akg, mg, nap, nmn; mutant

Details for d4ajra_

PDB Entry: 4ajr (more details), 2.69 Å

PDB Description: 3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with alpha-ketoglutarate, magnesium(II) and NADPH - The product complex
PDB Compounds: (A:) Isocitrate dehydrogenase [NADP]

SCOPe Domain Sequences for d4ajra_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4ajra_ c.77.1.1 (A:) automated matches {Escherichia coli [TaxId: 562]}

SCOPe Domain Coordinates for d4ajra_:

Click to download the PDB-style file with coordinates for d4ajra_.
(The format of our PDB-style files is described here.)

Timeline for d4ajra_: