SCOPe 2.05: Domain d3znsb_: 3zns B:

Lineage for d3znsb_ (3zns B:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.42: Arginase/deacetylase [52767] (1 superfamily)
   3 layers: a/b/a, parallel beta-sheet of 8 strands, order 21387456

4. Superfamily c.42.1: Arginase/deacetylase [52768] (3 families)

5. Family c.42.1.2: Histone deacetylase, HDAC [52773] (4 proteins)
   automatically mapped to Pfam PF00850

6. Protein Histone deacetylase 7, HDAC7 [159582] (1 species)
   HDAC7a

7. Species Human (Homo sapiens) [TaxId:9606] [159583] (5 PDB entries)
   Uniprot Q8WUI4 515-900

8. Domain d3znsb_: 3zns B: [218362]
   automated match to d3c0ya1
   complexed with k, nu7, zn

Details for d3znsb_

PDB Entry: 3zns, 2.45 Å

PDB Description: HDAC7 bound with TFMO inhibitor tmp942

PDB Compounds: (B:) histone deacetylase 7

SCOPe Domain Sequences for d3znsb_:

Sequence, based on SEQRES records:

>d3znsb_ c.42.1.2 (B:) Histone deacetylase 7, HDAC7 {Human (Homo sapiens) [TaxId: 9606]}
fttgliydsvmlkhqcscgdnsrhpehagriqsiwsrlqerglrsqceclrgrkasleel
qsvhserhvllygtnplsrlkldngklagllaqrmfvmlpcggvgvdtdtiwnelhssna
arwaagsvtdlafkvasrelkngfavvrppghhadhstamgfcffnsvaiacrqlqqqsk
askilivdwdvhhgngtqqtfyqdpsvlyislhrhddgnffpgsgavdevgagsgegfnv
nvawaggldppmgdpeylaafrivvmpiarefspdlvlvsagfdaaeghpaplggyhvsa
kcfgymtqqlmnlaggavvlalegghdltaicdaseacvaallgnrvdplseegwkqkpn
lnairsleavirvhskywgcmqr

Sequence, based on observed residues (ATOM records):

>d3znsb_ c.42.1.2 (B:) Histone deacetylase 7, HDAC7 {Human (Homo sapiens) [TaxId: 9606]}
fttgliydsvmlkhqcscgdnsrhpehagriqsiwsrlqerglrsqceclrgrkasleel
qsvhserhvllygtnplsrlkldngklagllaqvmlpcggvgvdtdtiwnelhssnaarw
aagsvtdlafkvasrelkngfavvrppghhadhstamgfcffnsvaiacrqlqqqskask
ilivdwdvhhgngtqqtfyqdpsvlyislhrhddgnffpgsgavdevgagsgegfnvnva
waggldppmgdpeylaafrivvmpiarefspdlvlvsagfdaaeghpaplggyhvsakcf
gymtqqlmnlaggavvlalegghdltaicdaseacvaallgnrvdplseegwkqkpnlna
irsleavirvhskywgcmqr

Timeline for d3znsb_:

• d3znsb_ first appeared in SCOPe 2.03
  
• d3znsb_ appears in SCOPe 2.04
  
• d3znsb_ appears in SCOPe 2.06
  
• d3znsb_ appears in the current release, SCOPe 2.08