SCOPe 2.05: Domain d3znrb_: 3znr B:

Lineage for d3znrb_ (3znr B:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.42: Arginase/deacetylase [52767] (1 superfamily)
   3 layers: a/b/a, parallel beta-sheet of 8 strands, order 21387456

4. Superfamily c.42.1: Arginase/deacetylase [52768] (3 families)

5. Family c.42.1.2: Histone deacetylase, HDAC [52773] (4 proteins)
   automatically mapped to Pfam PF00850

6. Protein Histone deacetylase 7, HDAC7 [159582] (1 species)
   HDAC7a

7. Species Human (Homo sapiens) [TaxId:9606] [159583] (5 PDB entries)
   Uniprot Q8WUI4 515-900

8. Domain d3znrb_: 3znr B: [218359]
   automated match to d3c0ya1
   complexed with k, nu9, zn

Details for d3znrb_

PDB Entry: 3znr, 2.4 Å

PDB Description: HDAC7 bound with inhibitor TMP269

PDB Compounds: (B:) histone deacetylase 7

SCOPe Domain Sequences for d3znrb_:

Sequence, based on SEQRES records:

>d3znrb_ c.42.1.2 (B:) Histone deacetylase 7, HDAC7 {Human (Homo sapiens) [TaxId: 9606]}
pfttgliydsvmlkhqcscgdnsrhpehagriqsiwsrlqerglrsqceclrgrkaslee
lqsvhserhvllygtnplsrlkldngklagllaqrmfvmlpcggvgvdtdtiwnelhssn
aarwaagsvtdlafkvasrelkngfavvrppghhadhstamgfcffnsvaiacrqlqqqs
kaskilivdwdvhhgngtqqtfyqdpsvlyislhrhddgnffpgsgavdevgagsgegfn
vnvawaggldppmgdpeylaafrivvmpiarefspdlvlvsagfdaaeghpaplggyhvs
akcfgymtqqlmnlaggavvlalegghdltaicdaseacvaallgnrvdplseegwkqkp
nlnairsleavirvhskywgcmqr

Sequence, based on observed residues (ATOM records):

>d3znrb_ c.42.1.2 (B:) Histone deacetylase 7, HDAC7 {Human (Homo sapiens) [TaxId: 9606]}
pfttgliydsvmlkhqcscgdnsrhpehagriqsiwsrlqerglrsqceclrgrkaslee
lqsvhserhvllygtnplsrlkldngklagllaqvmlpcggvgvdtdtiwnelhssnaar
waagsvtdlafkvasrelkngfavvrppghhadhstamgfcffnsvaiacrqlqqqskas
kilivdwdvhhgngtqqtfyqdpsvlyislhrhddgnffpgsgavdevgagsgegfnvnv
awaggldppmgdpeylaafrivvmpiarefspdlvlvsagfdaaeghpaplggyhvsakc
fgymtqqlmnlaggavvlalegghdltaicdaseacvaallgnrvdplseegwkqkpnln
airsleavirvhskywgcmqr

Timeline for d3znrb_:

• d3znrb_ first appeared in SCOPe 2.03
  
• d3znrb_ appears in SCOPe 2.04
  
• d3znrb_ appears in SCOPe 2.06
  
• d3znrb_ appears in the current release, SCOPe 2.08