Lineage for d3zkia_ (3zki A:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2058814Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2058815Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2061036Family b.50.1.0: automated matches [191552] (1 protein)
    not a true family
  6. 2061037Protein automated matches [190954] (10 species)
    not a true protein
  7. 2061062Species Human (Homo sapiens) [TaxId:9606] [193159] (12 PDB entries)
  8. 2061078Domain d3zkia_: 3zki A: [218295]
    automated match to d3zkga_
    complexed with wzv; mutant

Details for d3zkia_

PDB Entry: 3zki (more details), 2.4 Å

PDB Description: bace2 mutant structure with ligand
PDB Compounds: (A:) Beta-secretase 2

SCOPe Domain Sequences for d3zkia_:

Sequence, based on SEQRES records: (download)

>d3zkia_ b.50.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nflamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdters
styrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwng
ilglayatlakpsssletffdslvtqanipnvfsmqmcgaglpvagsgtnggslvlggie
pslykgdiwytpikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqkv
fdavveavaraslipafsdgfwtgsqlacwtnsetpwsyfpkisiylrdenssrsfriti
lpqlyiqpmmgaglnyecyrfgispstnalvigatvmegfyvifdraqkrvgfaaspcae
iagaavseisgpfstedvasncvp

Sequence, based on observed residues (ATOM records): (download)

>d3zkia_ b.50.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nflamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdters
styrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwng
ilglayatlakpsssletffdslvtqanipnvfsmqmcgagnggslvlggiepslykgdi
wytpikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqkvfdavveav
araslifsdgfwtgsqlacwtpwsyfpkisiylrdenssrsfritilpqlyiqpmmyecy
rfgispstnalvigatvmegfyvifdraqkrvgfaaspcaeiagaavseisgpfstedva
sncvp

SCOPe Domain Coordinates for d3zkia_:

Click to download the PDB-style file with coordinates for d3zkia_.
(The format of our PDB-style files is described here.)

Timeline for d3zkia_: