Lineage for d3vuza2 (3vuz A:194-362)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2072411Fold b.85: beta-clip [51268] (7 superfamilies)
    double-stranded ribbon sharply bent in two places; the ribbon ends form incomplete barrel; jelly-roll
  4. 2073020Superfamily b.85.7: SET domain [82199] (4 families) (S)
    duplication: the core is composed of two structural repeats similar to (circularly permuted) repeats of AFPIII
    also contains a substrate-binding alpha+beta subdomain inserted in the core
  5. 2073021Family b.85.7.1: Histone lysine methyltransferases [82200] (3 protein domains)
    contains metal-binding preSET and postSET domains
  6. 2073027Protein Histone H3 K4-specific methyltransferase SET7/9 catalytic domain [82205] (1 species)
  7. 2073028Species Human (Homo sapiens) [TaxId:9606] [82206] (18 PDB entries)
    Uniprot Q8WTS6 52-336
  8. 2073048Domain d3vuza2: 3vuz A:194-362 [218116]
    Other proteins in same PDB: d3vuza1, d3vuza3
    automated match to d3cbpa2
    complexed with k15

Details for d3vuza2

PDB Entry: 3vuz (more details), 2.5 Å

PDB Description: crystal structure of histone methyltransferase set7/9 in complex with aam-1
PDB Compounds: (A:) Histone-lysine N-methyltransferase SETD7

SCOPe Domain Sequences for d3vuza2:

Sequence, based on SEQRES records: (download)

>d3vuza2 b.85.7.1 (A:194-362) Histone H3 K4-specific methyltransferase SET7/9 catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
dkstsscistnallpdpyeservyvaeslissageglfskvavgpntvmsfyngvrithq
evdsrdwalngntlsldeetvidvpepynhvskycaslghkanhsftpnciydmfvhprf
gpikcirtlraveadeeltvaygydhsppgksgpeapewyqvelkafqa

Sequence, based on observed residues (ATOM records): (download)

>d3vuza2 b.85.7.1 (A:194-362) Histone H3 K4-specific methyltransferase SET7/9 catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
dkstsscistnallpdpyeservyvaeslissageglfskvavgpntvmsfyngvrithq
evdsrdwalngntlsldeetvidvpepynhvskycaslghkanhsftpnciydmfvhprf
gpikcirtlraveadeeltvaygydheapewyqvelkafqa

SCOPe Domain Coordinates for d3vuza2:

Click to download the PDB-style file with coordinates for d3vuza2.
(The format of our PDB-style files is described here.)

Timeline for d3vuza2: