SCOPe 2.03: Domain d3vqua_: 3vqu A:

Lineage for d3vqua_ (3vqu A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (18 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (314 PDB entries)

8. Domain d3vqua_: 3vqu A: [218043]
   automated match to d2pk9c_
   complexed with iod, o22

Details for d3vqua_

PDB Entry: 3vqu, 2.4 Å

PDB Description: crystal structure of human mps1 catalytic domain in complex with 4- [(4-amino-5-cyano-6-ethoxypyridin-2- yl)amino]benzamide

PDB Compounds: (A:) Dual specificity protein kinase TTK

SCOPe Domain Sequences for d3vqua_:

Sequence, based on SEQRES records:

>d3vqua_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ecisvkgriysilkqigsggsskvfqvlnekkqiyaikyvnleeadnqtldsyrneiayl
nklqqhsdkiirlydyeitdqyiymvmecgnidlnswlkkkksidpwerksywknmleav
htihqhgivhsdlkpanflivdgmlklidfgianqmqpdttsvvkdsqvgtvnymppeai
kdmsssrengkskskispksdvwslgcilyymtygktpfqqiinqisklhaiidpnheie
fpdipekdlqdvlkcclkrdpkqrisipellahpyvqiqt

Sequence, based on observed residues (ATOM records):

>d3vqua_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ecisvkgriysilkqigsggsskvfqvlnekkqiyaikyvnleadnqtldsyrneiayln
klqqhsdkiirlydyeitdqyiymvmecgnidlnswlkkkksidpwerksywknmleavh
tihqhgivhsdlkpanflivdgmlklidfgianqmqpdgtvnymppeaikdmsispksdv
wslgcilyymtygktpfqqiinqisklhaiidpnheiefpdipekdlqdvlkcclkrdpk
qrisipellahpyvqiqt

Timeline for d3vqua_:

• d3vqua_ is new in SCOPe 2.03-stable
  
• d3vqua_ appears in SCOPe 2.04
  
• d3vqua_ appears in the current release, SCOPe 2.08