SCOPe 2.06: Domain d3vq8b_: 3vq8 B:

Lineage for d3vq8b_ (3vq8 B:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (15 families)
   consists of one domain of this fold

5. Family c.55.3.2: Retroviral integrase, catalytic domain [53107] (2 proteins)

6. Protein Retroviral integrase, catalytic domain [53108] (4 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [53110] (53 PDB entries)

8. Domain d3vq8b_: 3vq8 B: [218028]
   automated match to d1bizb_
   protein/DNA complex; complexed with bcu, cd, cl, so4

Details for d3vq8b_

PDB Entry: 3vq8, 1.6 Å

PDB Description: HIV-1 IN core domain in complex with (3R)-3,4-dihydro-2H-chromen-3-ylmethanol

PDB Compounds: (B:) Pol polyprotein

SCOPe Domain Sequences for d3vq8b_:

Sequence, based on SEQRES records:

>d3vq8b_ c.55.3.2 (B:) Retroviral integrase, catalytic domain {Human immunodeficiency virus type 1 [TaxId: 11676]}
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftgatvraacdwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlktav
qmavfihnhkrkggiggysagerivdiiatdi

Sequence, based on observed residues (ATOM records):

>d3vq8b_ c.55.3.2 (B:) Retroviral integrase, catalytic domain {Human immunodeficiency virus type 1 [TaxId: 11676]}
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftgatvraacdwagikqesmnkelkkiigqvrdqaehlktavqmavfihnhkrgys
agerivdiiatdi

Timeline for d3vq8b_:

• d3vq8b_ first appeared in SCOPe 2.03
  
• d3vq8b_ appears in SCOPe 2.05
  
• d3vq8b_ appears in SCOPe 2.07
  
• d3vq8b_ appears in the current release, SCOPe 2.08