SCOPe 2.07: Domain d3vq6b_: 3vq6 B:

Lineage for d3vq6b_ (3vq6 B:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (16 families)
   consists of one domain of this fold

5. Family c.55.3.2: Retroviral integrase, catalytic domain [53107] (2 proteins)

6. Protein Retroviral integrase, catalytic domain [53108] (4 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [53110] (73 PDB entries)

8. Domain d3vq6b_: 3vq6 B: [218024]
   automated match to d2itga_
   protein/DNA complex; protein/RNA complex; complexed with bck, cd, so4

Details for d3vq6b_

PDB Entry: 3vq6, 1.8 Å

PDB Description: HIV-1 IN core domain in complex with (1-methyl-5-phenyl-1H-pyrazol-4-yl)methanol

PDB Compounds: (B:) Pol polyprotein

SCOPe Domain Sequences for d3vq6b_:

Sequence, based on SEQRES records:

>d3vq6b_ c.55.3.2 (B:) Retroviral integrase, catalytic domain {Human immunodeficiency virus type 1 [TaxId: 11676]}
sspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvht
dngsnftsttvkaacdwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlkta
vqmavfihnhkrkggiggysagerivdiiatdiq

Sequence, based on observed residues (ATOM records):

>d3vq6b_ c.55.3.2 (B:) Retroviral integrase, catalytic domain {Human immunodeficiency virus type 1 [TaxId: 11676]}
sspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvht
dngsnftsttvkaacdwagikqedgesmnkelkkiigqvrdqaehlktavqmavfihnhk
rkggiggysagerivdiiatdiq

Timeline for d3vq6b_:

• d3vq6b_ first appeared in SCOPe 2.03
  
• d3vq6b_ appears in SCOPe 2.06
  
• d3vq6b_ appears in the current release, SCOPe 2.08