SCOPe 2.06: Domain d3uzyb_: 3uzy B:

Lineage for d3uzyb_ (3uzy B:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families)

5. Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 proteins)
   Common fold covers whole protein structure

6. Protein automated matches [190169] (5 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188399] (45 PDB entries)

8. Domain d3uzyb_: 3uzy B: [217579]
   automated match to d3caqb_
   complexed with bdt, cl, nap; mutant

Details for d3uzyb_

PDB Entry: 3uzy, 1.83 Å

PDB Description: crystal structure of 5beta-reductase (akr1d1) e120h mutant in complex with nadp+ and 5beta-dihydrotestosterone

PDB Compounds: (B:) 3-oxo-5-beta-steroid 4-dehydrogenase

SCOPe Domain Sequences for d3uzyb_:

Sequence; same for both SEQRES and ATOM records:

>d3uzyb_ c.1.7.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dlsaashriplsdgnsipiiglgtysepkstpkgacatsvkvaidtgyrhidgayiyqne
hevgeairekiaegkvrredifycgklwatnhvpemvrptlertlrvlqldyvdlyiihv
pmafkpgdeiyprdengkwlyhksnlcatweameackdaglvkslgvsnfnrrqleliln
kpglkhkpvsnqvechpyftqpkllkfcqqhdivitaysplgtsrnpiwvnvssppllkd
allnslgkrynktaaqivlrfniqrgvvvipksfnlerikenfqifdfslteeemkdiea
lnknvrfvellmwrdhpeypfhdey

Timeline for d3uzyb_:

• d3uzyb_ first appeared in SCOPe 2.03
  
• d3uzyb_ appears in SCOPe 2.05
  
• d3uzyb_ appears in SCOPe 2.07
  
• d3uzyb_ appears in the current release, SCOPe 2.08