SCOPe 2.05: Domain d3tn8a_: 3tn8 A:

Lineage for d3tn8a_ (3tn8 A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Cell division protein kinase 9, CDK9 [160810] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [160811] (6 PDB entries)
   Uniprot P50750 8-325

8. Domain d3tn8a_: 3tn8 A: [216881]
   Other proteins in same PDB: d3tn8b1, d3tn8b2
   automated match to d3blha1
   complexed with f18, gol, po4

Details for d3tn8a_

PDB Entry: 3tn8, 2.95 Å

PDB Description: CDK9/cyclin T in complex with CAN508

PDB Compounds: (A:) Cyclin-dependent kinase 9

SCOPe Domain Sequences for d3tn8a_:

Sequence, based on SEQRES records:

>d3tn8a_ d.144.1.7 (A:) Cell division protein kinase 9, CDK9 {Human (Homo sapiens) [TaxId: 9606]}
vecpfcdevskyeklakigqgtfgevfkarhrktgqkvalkkvlmenekegfpitalrei
kilqllkhenvvnlieicrtkaspynrckgsiylvfdfcehdlagllsnvlvkftlseik
rvmqmllnglyyihrnkilhrdmkaanvlitrdgvlkladfglarafslaknsqpnrytn
rvvtlwyrppelllgerdygppidlwgagcimaemwtrspimqgnteqhqlalisqlcgs
itpevwpnvdnyelyeklelvkgqkrkvkdrlkayvrdpyaldlidkllvldpaqridsd
dalnhdffwsdpmpsdlk

Sequence, based on observed residues (ATOM records):

>d3tn8a_ d.144.1.7 (A:) Cell division protein kinase 9, CDK9 {Human (Homo sapiens) [TaxId: 9606]}
vecpfcdevskyeklakigqgtfgevfkarhrktgqkvalkkvlmenekegfpitalrei
kilqllkhenvvnlieicrtgsiylvfdfcehdlagllsnvlvkftlseikrvmqmllng
lyyihrnkilhrdmkaanvlitrdgvlkladfglarafslqpnrytnrvvtlwyrppell
lgerdygppidlwgagcimaemwtrspimqgnteqhqlalisqlcgsitpevwpnvdnye
lyeklelvkgqkrkvkdrlkayvrdpyaldlidkllvldpaqridsddalnhdffwsdpm
psdlk

Timeline for d3tn8a_:

• d3tn8a_ first appeared in SCOPe 2.03
  
• d3tn8a_ appears in SCOPe 2.04
  
• d3tn8a_ appears in SCOPe 2.06
  
• d3tn8a_ appears in the current release, SCOPe 2.08