SCOPe 2.07: Domain d3tmza1: 3tmz A:28-491

Lineage for d3tmza1 (3tmz A:28-491)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.1: Cytochrome P450 [48265] (23 proteins)

6. Protein Mammalian cytochrome p450 2b4 [101375] (1 species)

7. Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [101376] (10 PDB entries)
   Uniprot P00178

8. Domain d3tmza1: 3tmz A:28-491 [216878]
   Other proteins in same PDB: d3tmza2
   automated match to d1suoa_
   complexed with 06x, cm5, hem

Details for d3tmza1

PDB Entry: 3tmz, 2.25 Å

PDB Description: Crystal Structure of P450 2B4(H226Y) in complex with Amlodipine

PDB Compounds: (A:) Cytochrome P450 2B4

SCOPe Domain Sequences for d3tmza1:

Sequence, based on SEQRES records:

>d3tmza1 a.104.1.1 (A:28-491) Mammalian cytochrome p450 2b4 {Rabbit (Oryctolagus cuniculus) [TaxId: 9986]}
gklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlcgtdairea
lvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgkrsveeriq
eearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrlldlffqsfs
lissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldpsnprdfidv
yllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyphvtervqke
ieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrgyvipknte
vfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclgegiartelf
lffttilqnfsiaspvppedidltpresgvgnvppsyqirflar

Sequence, based on observed residues (ATOM records):

>d3tmza1 a.104.1.1 (A:28-491) Mammalian cytochrome p450 2b4 {Rabbit (Oryctolagus cuniculus) [TaxId: 9986]}
gklppgpsplpvlgnllqmdkgllrsflrlrekygdvftvylgsrpvvvlcgtdaireal
vdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfmgkrsveeriqee
arclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrlldlffqsfsli
ssfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldpsnprdfidvyl
lrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyphvtervqkeie
qvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrgyvipkntevf
pvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclgegiartelflf
fttilqnfsiaspvppedidltpresgvgnvppsyqirflar

Timeline for d3tmza1:

• d3tmza1 first appeared in SCOPe 2.03, called d3tmza_
  
• d3tmza1 appears in SCOPe 2.06