SCOPe 2.08: Domain d3t3fa2: 3t3f A:423-832

Lineage for d3t3fa2 (3t3f A:423-832)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (9 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.1: DNA polymerase I [56673] (5 proteins)
   in the multi-domain class (e), this applies to domains with different numbers of (sub)domains than the most common domain
   

6. Protein DNA polymerase I (Klenow fragment) [56674] (3 species)

7. Species Thermus aquaticus [TaxId:271] [56676] (29 PDB entries)

8. Domain d3t3fa2: 3t3f A:423-832 [216657]
   Other proteins in same PDB: d3t3fa1
   automated match to d1jxea2
   protein/DNA complex; complexed with fmt, gol, mg, n5p, na

Details for d3t3fa2

PDB Entry: 3t3f, 1.9 Å

PDB Description: Ternary Structure of the large fragment of Taq DNA polymerase bound to an abasic site and dNITP

PDB Compounds: (A:) DNA polymerase I, thermostable

SCOPe Domain Sequences for d3t3fa2:

Sequence, based on SEQRES records:

>d3t3fa2 e.8.1.1 (A:423-832) DNA polymerase I (Klenow fragment) {Thermus aquaticus [TaxId: 271]}
eerllwlyreverplsavlahmeatgvrldvaylralslevaeeiarleaevfrlaghpf
nlnsrdqlervlfdelglpaigktektgkrstsaavlealreahpivekilqyreltklk
styidplpdlihprtgrlhtrfnqtatatgrlsssdpnlqnipvrtplgqrirrafiaee
gwllvaldysqielrvlahlsgdenlirvfqegrdihtetaswmfgvpreavdplmrraa
ktinfgvlygmsahrlsqelaipyeeaqafieryfqsfpkvrawiektleegrrrgyvet
lfgrrryvpdlearvksvreaaermafnmpvqgtaadlmklamvklfprleemgarmllq
vhdelvleapkeraeavarlakevmegvyplavplevevgigedwlsake

Sequence, based on observed residues (ATOM records):

>d3t3fa2 e.8.1.1 (A:423-832) DNA polymerase I (Klenow fragment) {Thermus aquaticus [TaxId: 271]}
eerllwlyreverplsavlahmeatgvrldvaylralslevaeeiarleaevfrlaghpf
nlnsrdqlervlfdelglpaigktektgkrstsaavlealreahpivekilqyreltklk
styidplpdlihprtgrlhtrfnqtatatgrlsssdpnlqnipvrtplgqrirrafiaee
gwllvaldysqielrvlahlsgdenlirvfqegrdihtetaswmvdplmrraaktinfgv
lygmsahrlsqelaipyeeaqafieryfqsfpkvrawiektleegrrrgyvetlfgrrry
vpdlearvksvreaaermafnmpvqgtaadlmklamvklfprleemgarmllqvhdelvl
eapkeraeavarlakevmegvyplavplevevgigedwlsake

Timeline for d3t3fa2:

• d3t3fa2 first appeared in SCOPe 2.03
  
• d3t3fa2 appears in SCOPe 2.07