SCOPe 2.04: Domain d1a6ab1: 1a6a B:93-191

Lineage for d1a6ab1 (1a6a B:93-191)

1. Root: SCOPe 2.04

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Class II MHC beta chain, C-terminal domain [88625] (6 species)

7. Species Human (Homo sapiens), HLA-DR group [TaxId:9606] [88628] (40 PDB entries)
   Uniprot P04229 30-219
   probably orthologous to the mouse I-E group

8. Domain d1a6ab1: 1a6a B:93-191 [21616]
   Other proteins in same PDB: d1a6aa1, d1a6aa2, d1a6ab2
   complexed with nag

Details for d1a6ab1

PDB Entry: 1a6a, 2.75 Å

PDB Description: the structure of an intermediate in class ii mhc maturation: clip bound to hla-dr3

PDB Compounds: (B:) hla class II histocompatibility antigen, dr-1 beta chain

SCOPe Domain Sequences for d1a6ab1:

Sequence; same for both SEQRES and ATOM records:

>d1a6ab1 b.1.1.2 (B:93-191) Class II MHC beta chain, C-terminal domain {Human (Homo sapiens), HLA-DR group [TaxId: 9606]}
rrvhpkvtvypsktqplqhhnllvcsvsgfypgsievrwfrngqeektgvvstglihngd
wtfqtlvmletvprsgevytcqvehpsvtspltvewrar

Timeline for d1a6ab1:

• d1a6ab1 first appeared (with stable ids) in SCOP 1.55
  
• d1a6ab1 appears in SCOPe 2.03
  
• d1a6ab1 appears in SCOPe 2.05
  
• d1a6ab1 appears in the current release, SCOPe 2.08