SCOP 1.67: Domain d1a6aa1: 1a6a A:82-180

Lineage for d1a6aa1 (1a6a A:82-180)

1. Root: SCOP 1.67

2. Class b: All beta proteins [48724] (141 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (22 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (22 proteins)

6. Protein Class II MHC alpha chain, C-terminal domain [88618] (6 species)

7. Species Human (Homo sapiens), HLA-DR group [TaxId:9606] [88621] (25 PDB entries)
   probably orthologous to the mouse I-E group

8. Domain d1a6aa1: 1a6a A:82-180 [21615]
   Other proteins in same PDB: d1a6aa2, d1a6ab1, d1a6ab2
   complexed with nag

Details for d1a6aa1

PDB Entry: 1a6a, 2.75 Å

PDB Description: the structure of an intermediate in class ii mhc maturation: clip bound to hla-dr3

SCOP Domain Sequences for d1a6aa1:

Sequence; same for both SEQRES and ATOM records:

>d1a6aa1 b.1.1.2 (A:82-180) Class II MHC alpha chain, C-terminal domain {Human (Homo sapiens), HLA-DR group}
itnvppevtvltnspvelrepnvlicfidkftppvvnvtwlrngkpvttgvsetvflpre
dhlfrkfhylpflpstedvydcrvehwgldepllkhwef

Timeline for d1a6aa1:

• d1a6aa1 first appeared (with stable ids) in SCOP 1.55
  
• d1a6aa1 appears in SCOP 1.65
  
• d1a6aa1 appears in SCOP 1.69
  
• d1a6aa1 appears in the current release, SCOPe 2.08