SCOPe 2.05: Domain d3rv5a_: 3rv5 A:

Lineage for d3rv5a_ (3rv5 A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.39: EF Hand-like [47472] (4 superfamilies)
   core: 4 helices; array of 2 hairpins, opened

4. Superfamily a.39.1: EF-hand [47473] (12 families)
   Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop

5. Family a.39.1.5: Calmodulin-like [47502] (24 proteins)
   Duplication: made with two pairs of EF-hands

6. Protein Troponin C [47503] (6 species)

7. Species Human (Homo sapiens), cardiac isoform [TaxId:9606] [47508] (16 PDB entries)

8. Domain d3rv5a_: 3rv5 A: [216078]
   automated match to d1mxlc_
   complexed with ca, cd, dxc

Details for d3rv5a_

PDB Entry: 3rv5, 2.2 Å

PDB Description: Crystal structure of human cardiac troponin C regulatory domain in complex with cadmium and deoxycholic acid

PDB Compounds: (A:) troponin c, slow skeletal and cardiac muscles

SCOPe Domain Sequences for d3rv5a_:

Sequence; same for both SEQRES and ATOM records:

>d3rv5a_ a.39.1.5 (A:) Troponin C {Human (Homo sapiens), cardiac isoform [TaxId: 9606]}
diykaaveqlteeqknefkaafdifvlgaedgcistkelgkvmrmlgqnptpeelqemid
evdedgsgtvdfdeflvmmvrcm

Timeline for d3rv5a_:

• d3rv5a_ first appeared in SCOPe 2.03
  
• d3rv5a_ appears in SCOPe 2.04
  
• d3rv5a_ appears in SCOPe 2.06
  
• d3rv5a_ appears in the current release, SCOPe 2.08