SCOP 1.75: Domain d1fv1b1: 1fv1 B:93-190

Lineage for d1fv1b1 (1fv1 B:93-190)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)

6. Protein Class II MHC beta chain, C-terminal domain [88625] (6 species)

7. Species Human (Homo sapiens), HLA-DR group [TaxId:9606] [88628] (39 PDB entries)
   Uniprot P04229 30-219
   probably orthologous to the mouse I-E group

8. Domain d1fv1b1: 1fv1 B:93-190 [21606]
   Other proteins in same PDB: d1fv1a1, d1fv1a2, d1fv1b2, d1fv1d1, d1fv1d2, d1fv1e2

Details for d1fv1b1

PDB Entry: 1fv1, 1.9 Å

PDB Description: structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two hla-dr2 alleles

PDB Compounds: (B:) major histocompatibility complex beta chain

SCOP Domain Sequences for d1fv1b1:

Sequence; same for both SEQRES and ATOM records:

>d1fv1b1 b.1.1.2 (B:93-190) Class II MHC beta chain, C-terminal domain {Human (Homo sapiens), HLA-DR group [TaxId: 9606]}
rrvepkvtvypartqtlqhhnllvcsvngfypgsievrwfrnsqeekagvvstgliqngd
wtfqtlvmletvprsgevytcqvehpsvtspltvewra

Timeline for d1fv1b1:

• d1fv1b1 first appeared (with stable ids) in SCOP 1.55
  
• d1fv1b1 appears in SCOP 1.73
  
• d1fv1b1 appears in SCOPe 2.01
  
• d1fv1b1 appears in the current release, SCOPe 2.08