SCOPe 2.05: Domain d3rqnb_: 3rqn B:

Lineage for d3rqnb_ (3rqn B:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.174: Nitric oxide (NO) synthase oxygenase domain [56511] (1 superfamily)
   unusual fold

4. Superfamily d.174.1: Nitric oxide (NO) synthase oxygenase domain [56512] (1 family)
   automatically mapped to Pfam PF02898

5. Family d.174.1.1: Nitric oxide (NO) synthase oxygenase domain [56513] (2 proteins)

6. Protein Nitric oxide (NO) synthase oxygenase domain [56514] (6 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [82821] (205 PDB entries)
   Uniprot P29476 298-716

8. Domain d3rqnb_: 3rqn B: [216000]
   automated match to d1om4b_
   complexed with act, h4b, hem, y2f, zn

Details for d3rqnb_

PDB Entry: 3rqn, 1.95 Å

PDB Description: structure of the neuronal nitric oxide synthase heme domain in complex with 6-(((3*r*,4*r*)-4-(2-(((*s* )-1-(3-fluorophenyl)propan-2-yl) amino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine

PDB Compounds: (B:) Nitric oxide synthase, brain

SCOPe Domain Sequences for d3rqnb_:

Sequence, based on SEQRES records:

>d3rqnb_ d.174.1.1 (B:) Nitric oxide (NO) synthase oxygenase domain {Norway rat (Rattus norvegicus) [TaxId: 10116]}
rflkvknwetdvvltdtlhlkstletgctehicmgsimlpsqhtrkpedvrtkdqlfpla
kefldqyyssikrfgskahmdrleevnkeieststyqlkdteliygakhawrnasrcvgr
iqwsklqvfdardcttahgmfnyicnhvkyatnkgnlrsaitifpqrtdgkhdfrvwnsq
liryagykqpdgstlgdpanvqfteiciqqgwkaprgrfdvlplllqangndpelfqipp
elvlevpirhpkfdwfkdlglkwyglpavsnmlleigglefsacpfsgwymgteigvrdy
cdnsrynileevakkmdldmrktsslwkdqalveiniavlysfqsdkvtivdhhsatesf
ikhmeneyrcrggcpadwvwivppmsgsitpvfhqemlnyrltpsfeyqpdpwnthvwkg

Sequence, based on observed residues (ATOM records):

>d3rqnb_ d.174.1.1 (B:) Nitric oxide (NO) synthase oxygenase domain {Norway rat (Rattus norvegicus) [TaxId: 10116]}
rflkvknwetdvvltdtlhlkstletgctehicmgsimlpvrtkdqlfplakefldqyys
sikrfgskahmdrleevnkeieststyqlkdteliygakhawrnasrcvgriqwsklqvf
dardcttahgmfnyicnhvkyatnkgnlrsaitifpqrtdgkhdfrvwnsqliryagykq
pdgstlgdpanvqfteiciqqgwkaprgrfdvlplllqangndpelfqippelvlevpir
hpkfdwfkdlglkwyglpavsnmlleigglefsacpfsgwymgteigvrdycdnsrynil
eevakkmdldmrktsslwkdqalveiniavlysfqsdkvtivdhhsatesfikhmeneyr
crggcpadwvwivppmsgsitpvfhqemlnyrltpsfeyqpdpwnthvwkg

Timeline for d3rqnb_:

• d3rqnb_ first appeared in SCOPe 2.03
  
• d3rqnb_ appears in SCOPe 2.04
  
• d3rqnb_ appears in SCOPe 2.06
  
• d3rqnb_ appears in the current release, SCOPe 2.08