SCOPe 2.06: Domain d3qv8d3: 3qv8 D:358-498

Lineage for d3qv8d3 (3qv8 D:358-498)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.49: Pyruvate kinase C-terminal domain-like [52934] (2 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145, strand 5 is antiparallel to the rest

4. Superfamily c.49.1: PK C-terminal domain-like [52935] (2 families)

5. Family c.49.1.1: Pyruvate kinase, C-terminal domain [52936] (1 protein)
   automatically mapped to Pfam PF02887

6. Protein Pyruvate kinase, C-terminal domain [52937] (6 species)

7. Species Trypanosome (Leishmania mexicana) [TaxId:5665] [52940] (11 PDB entries)

8. Domain d3qv8d3: 3qv8 D:358-498 [215450]
   Other proteins in same PDB: d3qv8a1, d3qv8d1, d3qv8d2
   automated match to d1pkla3
   complexed with po4, s62

Details for d3qv8d3

PDB Entry: 3qv8, 2.45 Å

PDB Description: Crystal structure of Leishmania mexicana pyruvate kinase(LmPYK)in complex with benzothiazole-2,5-disulfonic acid.

PDB Compounds: (D:) pyruvate kinase

SCOPe Domain Sequences for d3qv8d3:

Sequence, based on SEQRES records:

>d3qv8d3 c.49.1.1 (D:358-498) Pyruvate kinase, C-terminal domain {Trypanosome (Leishmania mexicana) [TaxId: 5665]}
neyvffnsikklqhipmsadeavcssavnsvyetkakamvvlsntgrsarlvakyrpncp
ivcvttrlqtcrqlnitqgvesvffdadklghdegkehrvaagvefakskgyvqtgdycv
vihadhkvkgyanqtrillve

Sequence, based on observed residues (ATOM records):

>d3qv8d3 c.49.1.1 (D:358-498) Pyruvate kinase, C-terminal domain {Trypanosome (Leishmania mexicana) [TaxId: 5665]}
neyvffnsikklqhipmsadeavcssavnsvyetkakamvvlsntgrsarlvakyrpncp
ivcvttrlqtcrqlnitqgvesvffdadklghdegkehrvaagvefakskgyvqtgdycv
vihadanqtrillve

Timeline for d3qv8d3:

• d3qv8d3 first appeared in SCOPe 2.03
  
• d3qv8d3 appears in SCOPe 2.05
  
• d3qv8d3 appears in SCOPe 2.07
  
• d3qv8d3 appears in the current release, SCOPe 2.08