Lineage for d3qd4a_ (3qd4 A:)

  1. Root: SCOPe 2.03
  2. 1396887Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1433536Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1433537Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1436359Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 1436360Protein automated matches [190417] (18 species)
    not a true protein
  7. 1436481Species Human (Homo sapiens) [TaxId:9606] [187294] (314 PDB entries)
  8. 1436684Domain d3qd4a_: 3qd4 A: [215183]
    automated match to d4eopc_
    complexed with 3q6, so4

Details for d3qd4a_

PDB Entry: 3qd4 (more details), 2.3 Å

PDB Description: Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with 1,1-Dimethylethyl{(3R,5R)-1-[2-amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-5-methyl-3-piperidinyl}carbamate
PDB Compounds: (A:) 3-phosphoinositide-dependent protein kinase 1

SCOPe Domain Sequences for d3qd4a_:

Sequence, based on SEQRES records: (download)

>d3qd4a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ppqprkkrpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtre
rdvmsrldhpffvklyftfqddeklyfglsyakngellkyirkigsfdetctrfytaeiv
saleylhgkgiihrdlkpenillnedmhiqitdfgtakvlspeskqaransfvgtaqyvs
pellteksackssdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkar
dlvekllvldatkrlgceemegygplkahpffesvtwenlhqqtppkl

Sequence, based on observed residues (ATOM records): (download)

>d3qd4a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ppqprkkrpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtre
rdvmsrldhpffvklyftfqddeklyfglsyakngellkyirkigsfdetctrfytaeiv
saleylhgkgiihrdlkpenillnedmhiqitdfgtakvlsgtaqyvspellteksacks
sdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkardlvekllvldat
krlgceemegygplkahpffesvtwenlhqqtppkl

SCOPe Domain Coordinates for d3qd4a_:

Click to download the PDB-style file with coordinates for d3qd4a_.
(The format of our PDB-style files is described here.)

Timeline for d3qd4a_: