SCOPe 2.08: Domain d3qd4a_: 3qd4 A:

Lineage for d3qd4a_ (3qd4 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d3qd4a_: 3qd4 A: [215183]
   automated match to d4eopc_
   complexed with 3q6, so4

Details for d3qd4a_

PDB Entry: 3qd4, 2.3 Å

PDB Description: Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with 1,1-Dimethylethyl{(3R,5R)-1-[2-amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-5-methyl-3-piperidinyl}carbamate

PDB Compounds: (A:) 3-phosphoinositide-dependent protein kinase 1

SCOPe Domain Sequences for d3qd4a_:

Sequence, based on SEQRES records:

>d3qd4a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ppqprkkrpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtre
rdvmsrldhpffvklyftfqddeklyfglsyakngellkyirkigsfdetctrfytaeiv
saleylhgkgiihrdlkpenillnedmhiqitdfgtakvlspeskqaransfvgtaqyvs
pellteksackssdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkar
dlvekllvldatkrlgceemegygplkahpffesvtwenlhqqtppkl

Sequence, based on observed residues (ATOM records):

>d3qd4a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ppqprkkrpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtre
rdvmsrldhpffvklyftfqddeklyfglsyakngellkyirkigsfdetctrfytaeiv
saleylhgkgiihrdlkpenillnedmhiqitdfgtakvlsgtaqyvspellteksacks
sdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkardlvekllvldat
krlgceemegygplkahpffesvtwenlhqqtppkl

Timeline for d3qd4a_:

• d3qd4a_ first appeared in SCOPe 2.03
  
• d3qd4a_ appears in SCOPe 2.07