SCOPe 2.03: Domain d3qd0a_: 3qd0 A:

Lineage for d3qd0a_ (3qd0 A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (18 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (314 PDB entries)

8. Domain d3qd0a_: 3qd0 A: [215181]
   automated match to d4eopc_
   complexed with 3q4, gol, so4

Details for d3qd0a_

PDB Entry: 3qd0, 1.99 Å

PDB Description: Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with (2R,5S)-1-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-6-methyl-N-phenyl-3-piperidinecarboxamide

PDB Compounds: (A:) 3-phosphoinositide-dependent protein kinase 1

SCOPe Domain Sequences for d3qd0a_:

Sequence, based on SEQRES records:

>d3qd0a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qprkkrpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtrerd
vmsrldhpffvklyftfqddeklyfglsyakngellkyirkigsfdetctrfytaeivsa
leylhgkgiihrdlkpenillnedmhiqitdfgtakvlspeskqaransfvgtaqyvspe
llteksackssdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkardl
vekllvldatkrlgceemegygplkahpffesvtwenlhqqtppkl

Sequence, based on observed residues (ATOM records):

>d3qd0a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qprkkrpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtrerd
vmsrldhpffvklyftfqddeklyfglsyakngellkyirkigsfdetctrfytaeivsa
leylhgkgiihrdlkpenillnedmhiqitdfgtakvlsgtaqyvspellteksackssd
lwalgciiyqlvaglppfragneylifqkiikleydfpekffpkardlvekllvldatkr
lgceemegygplkahpffesvtwenlhqqtppkl

Timeline for d3qd0a_:

• d3qd0a_ is new in SCOPe 2.03-stable
  
• d3qd0a_ appears in SCOPe 2.04
  
• d3qd0a_ appears in the current release, SCOPe 2.08