SCOPe 2.04: Domain d3qcma_: 3qcm A:

Lineage for d3qcma_ (3qcm A:)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.0: automated matches [191381] (1 protein)
   not a true family

6. Protein automated matches [190475] (6 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187400] (86 PDB entries)

8. Domain d3qcma_: 3qcm A: [215164]
   automated match to d1yfoa_
   complexed with mes, nxw

Details for d3qcma_

PDB Entry: 3qcm, 2.4 Å

PDB Description: Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 2-[(3,4-dichlorobenzyl)sulfanyl]-4-{[3-({N-[2-(methylamino)ethyl]glycyl}amino)phenyl]ethynyl}benzoic acid

PDB Compounds: (A:) Receptor-type tyrosine-protein phosphatase gamma

SCOPe Domain Sequences for d3qcma_:

Sequence, based on SEQRES records:

>d3qcma_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
meaipvkqfvkhigelysnnqhgfsedfeevqrctadmnitaehsnhpenkhknryinil
aydhsrvklrplpgkdskhsdyinanyvdgynkakayiatqgplkstfedfwrmiweqnt
giiimitnlvekgrrkcdqywptenteeygniivtlkstkihacytvrrfsirntkvkkg
qkgnpkgrqnervviqyhytqwpdmgvpeyalpvltfvrrssaarmpetgpvlvhcsagv
grtgtyividsmlqqikdkstvnvlgflkhirtqrnylvqteeqyifihdalleailgk

Sequence, based on observed residues (ATOM records):

>d3qcma_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
meaipvkqfvkhigelysnnqhgfsedfeevqrctadmnitaehsnhpenkhknryinil
aydhsrvklrplpgskhsdyinanyvdgynkakayiatqgplkstfedfwrmiweqntgi
iimitnlvekgrrkcdqywptenteeygniivtlkstkihacytvrrfsirntkvqnerv
viqyhytqwpdmgvpeyalpvltfvrrssaarmpetgpvlvhcsagvgrtgtyividsml
qqikdkstvnvlgflkhirtqrnylvqteeqyifihdalleailgk

Timeline for d3qcma_:

• d3qcma_ first appeared in SCOPe 2.03
  
• d3qcma_ appears in SCOPe 2.05
  
• d3qcma_ appears in the current release, SCOPe 2.08