SCOPe 2.04: Domain d3qcfb_: 3qcf B:

Lineage for d3qcfb_ (3qcf B:)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.0: automated matches [191381] (1 protein)
   not a true family

6. Protein automated matches [190475] (6 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187400] (86 PDB entries)

8. Domain d3qcfb_: 3qcf B: [215157]
   automated match to d1yfoa_
   complexed with nxy, so4

Details for d3qcfb_

PDB Entry: 3qcf, 2.5 Å

PDB Description: Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 3-[(3,4-dichlorobenzyl)sulfanyl]thiophene-2-carboxylic acid via co-crystallization

PDB Compounds: (B:) Receptor-type tyrosine-protein phosphatase gamma

SCOPe Domain Sequences for d3qcfb_:

Sequence, based on SEQRES records:

>d3qcfb_ c.45.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
meaipvkqfvkhigelysnnqhgfsedfeevqrctadmnitaehsnhpenkhknryinil
aydhsrvklrplpgkdskhsdyinanyvdgynkakayiatqgplkstfedfwrmiweqnt
giivmitnlvekgrrkcdqywptenseeygniivtlkstkihacytvrrfsirntkvkkg
qkgnpkgrqnervviqyhytqwpdmgvpeyalpvltfvrrssaarmpetgpvlvhcsagv
grtgtyividsmlqqikdkstvnvlgflkhirtqrnylvqteeqyifihdalleailg

Sequence, based on observed residues (ATOM records):

>d3qcfb_ c.45.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
meaipvkqfvkhigelysnnqhgfsedfeevqrctadmnitaehsnhpenkhknryinil
aydhsrvklrplpgkskhsdyinanyvdgynkakayiatqgplkstfedfwrmiweqntg
iivmitnlvekgrrkcdqywptenseeygniivtlkstkihacytvrrfsirntknervv
iqyhytqwpdmgvpeyalpvltfvrrssaarmpetgpvlvhcsagvgrtgtyividsmlq
qikdkstvnvlgflkhirtqrnylvqteeqyifihdalleailg

Timeline for d3qcfb_:

• d3qcfb_ first appeared in SCOPe 2.03
  
• d3qcfb_ appears in SCOPe 2.05
  
• d3qcfb_ appears in the current release, SCOPe 2.08