SCOPe 2.05: Domain d3pxba2: 3pxb A:1758-1859

Lineage for d3pxba2 (3pxb A:1758-1859)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.15: BRCT domain [52112] (1 superfamily)
   3 layers, a/b/a; core: parallel beta-sheet of 4 strands, order 2134

4. Superfamily c.15.1: BRCT domain [52113] (6 families)
   Pfam PF00533

5. Family c.15.1.3: BRCT domain [63955] (1 protein)

6. Protein Breast cancer associated protein, BRCA1 [63956] (2 species)
   duplication: tandem repeat of BRCT domain

7. Species Human (Homo sapiens) [TaxId:9606] [63957] (15 PDB entries)
   Uniprot P38398 1649-1863

8. Domain d3pxba2: 3pxb A:1758-1859 [214967]
   automated match to d1t15a2
   complexed with ni, so4

Details for d3pxba2

PDB Entry: 3pxb, 2.5 Å

PDB Description: impact of brca1 brct domain missense substitutions on phospho-peptide recognition: t1700a

PDB Compounds: (A:) breast cancer type 1 susceptibility protein

SCOPe Domain Sequences for d3pxba2:

Sequence, based on SEQRES records:

>d3pxba2 c.15.1.3 (A:1758-1859) Breast cancer associated protein, BRCA1 {Human (Homo sapiens) [TaxId: 9606]}
rkifrgleiccygpftnmptdqlewmvqlcgasvvkelssftlgtgvhpivvvqpdawte
dngfhaigqmceapvvtrewvldsvalyqcqeldtylipqip

Sequence, based on observed residues (ATOM records):

>d3pxba2 c.15.1.3 (A:1758-1859) Breast cancer associated protein, BRCA1 {Human (Homo sapiens) [TaxId: 9606]}
rkifrgleiccygpftnmptdqlewmvqlcgasvvkelssftlgtgvhpivvvqpdawtg
fhaigqmceapvvtrewvldsvalyqcqeldtylipqip

Timeline for d3pxba2:

• d3pxba2 first appeared in SCOPe 2.03
  
• d3pxba2 appears in SCOPe 2.04
  
• d3pxba2 appears in SCOPe 2.06
  
• d3pxba2 appears in the current release, SCOPe 2.08