SCOPe 2.08: Domain d3pr0b_: 3pr0 B:

Lineage for d3pr0b_ (3pr0 B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.117: Amidase signature (AS) enzymes [75303] (1 superfamily)
   possible duplication: the topologies of N- and C-terminal halves are similar; 3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213549A867 (A=10); strands from 5 to 9 are antiparallel to the rest

4. Superfamily c.117.1: Amidase signature (AS) enzymes [75304] (1 family)
   automatically mapped to Pfam PF01425

5. Family c.117.1.1: Amidase signature (AS) enzymes [75305] (5 proteins)

6. Protein automated matches [191046] (2 species)
   not a true protein

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [188885] (20 PDB entries)

8. Domain d3pr0b_: 3pr0 B: [214934]
   automated match to d2wapb_
   complexed with cl, jg2, peg

Details for d3pr0b_

PDB Entry: 3pr0, 2.2 Å

PDB Description: Crystal Structure of a Covalently Bound alpha-Ketoheterocycle Inhibitor (Phenhexyl/Oxadiazole/Pyridine) to a Humanized Variant of Fatty Acid Amide Hydrolase

PDB Compounds: (B:) fatty acid amide hydrolase 1

SCOPe Domain Sequences for d3pr0b_:

Sequence; same for both SEQRES and ATOM records:

>d3pr0b_ c.117.1.1 (B:) automated matches {Norway rat (Rattus norvegicus) [TaxId: 10116]}
wtgrqkargaatrarqkqrasletmdkavqrfrlqnpdldsealltlpllqlvqklqsge
lspeavfftylgkawevnkgtncvtsyltdcetqlsqaprqgllygvpvslkecfsykgh
dstlglslnegmpsesdcvvvqvlklqgavpfvhtnvpqsmfsydcsnplfgqtmnpwks
skspggssggegaligsggsplglgtdiggsirfpsafcgicglkptgnrlsksglkgcv
ygqtavqlslgpmardveslalclkallcehlftldptvpplpfreevyrssrplrvgyy
etdnytmpspamrralietkqrleaaghtlipflpnnipyalevlstgglfsdggrsflq
nfkgdfvdpclgdlililrlpswfkrllslllkplfprlaaflnnmrprsaeklwklqhe
iemyrqsviaqwkamnldvlltpmlgpaldlntpgratgavsytmlyncldfpagvvpvt
tvtaeddaqmelykgyfgdiwdiilkkamknsvglpvavqcvalpwqeelclrfmreveq
lmtpqkqp

Timeline for d3pr0b_:

• d3pr0b_ first appeared in SCOPe 2.03
  
• d3pr0b_ appears in SCOPe 2.07