SCOPe 2.06: Domain d3otua_: 3otu A:

Lineage for d3otua_ (3otu A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (25 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (882 PDB entries)

8. Domain d3otua_: 3otu A: [214553]
   automated match to d4eopc_
   complexed with bi4, cl, j30, so4; mutant

Details for d3otua_

PDB Entry: 3otu, 2.1 Å

PDB Description: PDK1 mutant bound to allosteric disulfide fragment activator JS30

PDB Compounds: (A:) 3-phosphoinositide-dependent protein kinase 1

SCOPe Domain Sequences for d3otua_:

Sequence, based on SEQRES records:

>d3otua_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
krpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtrerdvmsr
ldhpffvklyfcfqddeklyfglsyakngellkyirkigsfdetctrfytaeivsaleyl
hgkgiihrdlkpenillnedmhiqitdfgtakvlspeskqaransfvgtaqyvspellte
ksackssdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkardlvekl
lvldatkrlgceemegygplkahpffesvtwenlhqqtppklt

Sequence, based on observed residues (ATOM records):

>d3otua_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
krpedfkfgkilgesfstvvlarelatsreyaikilekrhiikenkvpyvtrerdvmsrl
dhpffvklyfcfqddeklyfglsyakngellkyirkigsfdetctrfytaeivsaleylh
gkgiihrdlkpenillnedmhiqitdfgtakvlsaransfvgtaqyvspellteksacks
sdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkardlvekllvldat
krlgceemegygplkahpffesvtwenlhqqtppklt

Timeline for d3otua_:

• d3otua_ first appeared in SCOPe 2.03
  
• d3otua_ appears in SCOPe 2.05
  
• d3otua_ appears in SCOPe 2.07
  
• d3otua_ appears in the current release, SCOPe 2.08