SCOPe 2.07: Domain d3orxb_: 3orx B:

Lineage for d3orxb_ (3orx B:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (35 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1319 PDB entries)

8. Domain d3orxb_: 3orx B: [214505]
   automated match to d4eopc_
   complexed with 1f8, cl; mutant

Details for d3orxb_

PDB Entry: 3orx, 2.2 Å

PDB Description: PDK1 mutant bound to allosteric disulfide fragment inhibitor 1F8

PDB Compounds: (B:) 3-phosphoinositide-dependent protein kinase 1

SCOPe Domain Sequences for d3orxb_:

Sequence, based on SEQRES records:

>d3orxb_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
krpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtrerdvmsr
ldhpffvklyfcfqddeklyfglsyakngellkyirkigsfdetctrfytaeivsaleyl
hgkgiihrdlkpenillnedmhiqitdfgtakvlspeskqaransfvgtaqyvspellte
ksackssdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkardlvekl
lvldatkrlgceemegygplkahpffesvtwenlhqqtppklt

Sequence, based on observed residues (ATOM records):

>d3orxb_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
krpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtrerdvmsr
ldhpffvklyfcfqddeklyfglsyakngellkyirkigsfdetctrfytaeivsaleyl
hgkgiihrdlkpenillnedmhiqitdfgtakvlspeskqansfvgtaqyvspellteks
ackssdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkardlvekllv
ldatkrlgceemegygplkahpffesvtwenlhqqtppklt

Timeline for d3orxb_:

• d3orxb_ first appeared in SCOPe 2.03
  
• d3orxb_ appears in SCOPe 2.06
  
• d3orxb_ appears in the current release, SCOPe 2.08