SCOPe 2.06: Domain d3of0b_: 3of0 B:

Lineage for d3of0b_ (3of0 B:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein c-src tyrosine kinase [56155] (2 species)
   PTK group; Src subfamily; non-membrane spanning protein tyrosine kinase

7. Species Chicken (Gallus gallus) [TaxId:9031] [56157] (48 PDB entries)

8. Domain d3of0b_: 3of0 B: [214327]
   automated match to d2gqgb_
   mutant

Details for d3of0b_

PDB Entry: 3of0, 2.7 Å

PDB Description: crystal structure of the L317I mutant of the chicken c-Src tyrosine kinase domain

PDB Compounds: (B:) Proto-oncogene tyrosine-protein kinase Src

SCOPe Domain Sequences for d3of0b_:

Sequence, based on SEQRES records:

>d3of0b_ d.144.1.7 (B:) c-src tyrosine kinase {Chicken (Gallus gallus) [TaxId: 9031]}
kdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqeaqvmkk
irheklvqlyavvseepiyivteymskgslldflkgemgkylrlpqlvdmaaqiasgmay
vermnyvhrdlraanilvgenlvckvadfglarliedneytarqgakfpikwtapeaaly
grftiksdvwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmc
qcwrkdpeerptfeylqafledyftstepqyqpgenl

Sequence, based on observed residues (ATOM records):

>d3of0b_ d.144.1.7 (B:) c-src tyrosine kinase {Chicken (Gallus gallus) [TaxId: 9031]}
kdaweipreslrlevklgqgcfgevwmgtwngttrvaiktmspeaflqeaqvmkkirhek
lvqlyavvsyivteymskgslldflkgemgkylrlpqlvdmaaqiasgmayvermnyvhr
dlraanilvgenlvckvadfgfpikwtapeaalygrftiksdvwsfgilltelttkgrvp
ypgmvnrevldqvergyrmpcppecpeslhdlmcqcwrkdpeerptfeylqafledyfts
tepqyqpgenl

Timeline for d3of0b_:

• d3of0b_ first appeared in SCOPe 2.03
  
• d3of0b_ appears in SCOPe 2.05
  
• d3of0b_ appears in SCOPe 2.07
  
• d3of0b_ appears in the current release, SCOPe 2.08