SCOPe 2.06: Domain d3o6fa2: 3o6f A:82-181

Lineage for d3o6fa2 (3o6f A:82-181)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Class II MHC alpha chain, C-terminal domain [88618] (6 species)

7. Species Human (Homo sapiens), HLA-DR group [TaxId:9606] [88621] (37 PDB entries)
   Uniprot P01903 28-207
   probably orthologous to the mouse I-E group

8. Domain d3o6fa2: 3o6f A:82-181 [214201]
   Other proteins in same PDB: d3o6fa1, d3o6fc1, d3o6fc2, d3o6fd1, d3o6fd2, d3o6fe1, d3o6fg1, d3o6fg2, d3o6fh1, d3o6fh2
   automated match to d1pywa1

Details for d3o6fa2

PDB Entry: 3o6f, 2.8 Å

PDB Description: crystal structure of a human autoimmune tcr ms2-3c8 bound to mhc class ii self-ligand mbp/hla-dr4

PDB Compounds: (A:) hla class II histocompatibility antigen, dr alpha chain

SCOPe Domain Sequences for d3o6fa2:

Sequence; same for both SEQRES and ATOM records:

>d3o6fa2 b.1.1.2 (A:82-181) Class II MHC alpha chain, C-terminal domain {Human (Homo sapiens), HLA-DR group [TaxId: 9606]}
itnvppevtvltnspvelrepnvlicfidkftppvvnvtwlrngkpvttgvsetvflpre
dhlfrkfhylpflpstedvydcrvehwgldepllkhwefd

Timeline for d3o6fa2:

• d3o6fa2 first appeared in SCOPe 2.03
  
• d3o6fa2 appears in SCOPe 2.05
  
• d3o6fa2 appears in SCOPe 2.07
  
• d3o6fa2 appears in the current release, SCOPe 2.08