SCOPe 2.07: Domain d3o11l2: 3o11 L:106-212

Lineage for d3o11l2 (3o11 L:106-212)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88569] (151 PDB entries)
   including humanized antibodies (chimeric proteins with human constant domains)
   SQ NA # humanized antibody ! Uniprot P01834 # KAC_HUMAN Ig kappa chain C region ! SQ P01834 # KAC_HUMAN Ig kappa chain C region. ! SQ NA # engineered antibody

8. Domain d3o11l2: 3o11 L:106-212 [214112]
   Other proteins in same PDB: d3o11a1, d3o11l1
   automated match to d1rhha2

Details for d3o11l2

PDB Entry: 3o11, 2.8 Å

PDB Description: anti-beta-amyloid antibody c706 fab in space group c2

PDB Compounds: (L:) C706 LIGHT CHAIN variable region, Ig kappa chain C region chimera

SCOPe Domain Sequences for d3o11l2:

Sequence; same for both SEQRES and ATOM records:

>d3o11l2 b.1.1.2 (L:106-212) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens) [TaxId: 9606]}
rtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqd
skdstyslsstltlskadyekhkvyacevthqglsspvtksfnrgec

Timeline for d3o11l2:

• d3o11l2 first appeared in SCOPe 2.03
  
• d3o11l2 appears in SCOPe 2.06
  
• d3o11l2 appears in the current release, SCOPe 2.08