SCOPe 2.08: Domain d3ntgb2: 3ntg B:59-569

Lineage for d3ntgb2 (3ntg B:59-569)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.93: Heme-dependent peroxidases [48112] (1 superfamily)
   multihelical; consists of two all-alpha domains

4. Superfamily a.93.1: Heme-dependent peroxidases [48113] (4 families)

5. Family a.93.1.2: Myeloperoxidase-like [48132] (3 proteins)

6. Protein Prostaglandin H2 synthase [48136] (2 species)
   contains EGF-like module

7. Species Mouse (Mus musculus) [TaxId:10090] [48138] (13 PDB entries)

8. Domain d3ntgb2: 3ntg B:59-569 [214048]
   Other proteins in same PDB: d3ntga1, d3ntgb1, d3ntgc1, d3ntgd1
   automated match to d1ddxa1
   complexed with bog, d72, hem, nag

Details for d3ntgb2

PDB Entry: 3ntg, 2.19 Å

PDB Description: crystal structure of cox-2 with selective compound 23d-(r)

PDB Compounds: (B:) Prostaglandin G/H synthase 2

SCOPe Domain Sequences for d3ntgb2:

Sequence; same for both SEQRES and ATOM records:

>d3ntgb2 a.93.1.2 (B:59-569) Prostaglandin H2 synthase {Mouse (Mus musculus) [TaxId: 10090]}
fltriklllkptpntvhyilthfkgvwnivnnipflrslimkyvltsrsylidspptynv
hygyksweafsnlsyytralppvaddcptpmgvkgnkelpdskevlekvllrrefipdpq
gsnmmfaffaqhfthqffktdhkrgpgftrglghgvdlnhiygetldrqhklrlfkdgkl
kyqviggevypptvkdtqvemiypphipenlqfavgqevfglvpglmmyatiwlrehnrv
cdilkqehpewgdeqlfqtsrliligetikiviedyvqhlsgyhfklkfdpellfnqqfq
yqnriasefntlyhwhpllpdtfniedqeysfkqflynnsillehgltqfvesftrqiag
rvaggrnvpiavqavakasidqsremkyqslneyrkrfslkpytsfeeltgekemaaelk
alysdidvmelypallvekprpdaifgetmvelgapfslkglmgnpicspqywkpstfgg
evgfkiintasiqslicnnvkgcpftsfnvq

Timeline for d3ntgb2:

• d3ntgb2 first appeared in SCOPe 2.03
  
• d3ntgb2 appears in SCOPe 2.07