SCOPe 2.06: Domain d3n8xb2: 3n8x B:74-584

Lineage for d3n8xb2 (3n8x B:74-584)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.93: Heme-dependent peroxidases [48112] (1 superfamily)
   multihelical; consists of two all-alpha domains

4. Superfamily a.93.1: Heme-dependent peroxidases [48113] (4 families)

5. Family a.93.1.2: Myeloperoxidase-like [48132] (3 proteins)

6. Protein Prostaglandin H2 synthase [48136] (2 species)
   contains EGF-like module

7. Species Sheep (Ovis aries) [TaxId:9940] [48137] (23 PDB entries)
   Uniprot P05979 32-584

8. Domain d3n8xb2: 3n8x B:74-584 [213822]
   Other proteins in same PDB: d3n8xa1, d3n8xb1
   automated match to d1q4ga1
   complexed with bog, hem, nag, nim

Details for d3n8xb2

PDB Entry: 3n8x, 2.75 Å

PDB Description: crystal structure of cyclooxygenase-1 in complex with nimesulide

PDB Compounds: (B:) Prostaglandin G/H synthase 1

SCOPe Domain Sequences for d3n8xb2:

Sequence; same for both SEQRES and ATOM records:

>d3n8xb2 a.93.1.2 (B:74-584) Prostaglandin H2 synthase {Sheep (Ovis aries) [TaxId: 9940]}
iwtwlrttlrpspsfihfllthgrwlwdfvnatfirdtlmrlvltvrsnlipspptynia
hdyiswesfsnvsyytrilpsvprdcptpmgtkgkkqlpdaeflsrrfllrrkfipdpqg
tnlmfaffaqhfthqffktsgkmgpgftkalghgvdlghiygdnlerqyqlrlfkdgklk
yqmlngevyppsveeapvlmhyprgippqsqmavgqevfgllpglmlyatiwlrehnrvc
dllkaehptwgdeqlfqtarliligetikivieeyvqqlsgyflqlkfdpellfgaqfqy
rnriamefnqlyhwhplmpdsfrvgpqdysyeqflfntsmlvdygvealvdafsrqpagr
igggrnidhhilhvavdvikesrvlrlqpfneyrkrfgmkpytsfqeltgekemaaelee
lygdidalefypglllekchpnsifgesmiemgapfslkgllgnpicspeywkastfgge
vgfnlvktatlkklvclntktcpyvsfhvpd

Timeline for d3n8xb2:

• d3n8xb2 first appeared in SCOPe 2.03
  
• d3n8xb2 appears in SCOPe 2.05
  
• d3n8xb2 appears in SCOPe 2.07
  
• d3n8xb2 appears in the current release, SCOPe 2.08