SCOPe 2.05: Domain d3n6ga_: 3n6g A:

Lineage for d3n6ga_ (3n6g A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.174: Nitric oxide (NO) synthase oxygenase domain [56511] (1 superfamily)
   unusual fold

4. Superfamily d.174.1: Nitric oxide (NO) synthase oxygenase domain [56512] (1 family)
   automatically mapped to Pfam PF02898

5. Family d.174.1.1: Nitric oxide (NO) synthase oxygenase domain [56513] (2 proteins)

6. Protein Nitric oxide (NO) synthase oxygenase domain [56514] (6 species)

7. Species Cow (Bos taurus) [TaxId:9913] [56517] (85 PDB entries)
   Uniprot P29473 67-482

8. Domain d3n6ga_: 3n6g A: [213778]
   automated match to d3hsnb_
   complexed with act, cad, gol, h4b, hem, xfk, zn; mutant

Details for d3n6ga_

PDB Entry: 3n6g, 2.21 Å

PDB Description: structure of endothelial nitric oxide synthase n368d single mutant heme domain complexed with 4-(2-(5-(2-(6-amino-4-methylpyridin-2-yl) ethyl)pyridin-3-yl)ethyl)-6-methylpyridin-2-amine

PDB Compounds: (A:) nitric oxide synthase

SCOPe Domain Sequences for d3n6ga_:

Sequence, based on SEQRES records:

>d3n6ga_ d.174.1.1 (A:) Nitric oxide (NO) synthase oxygenase domain {Cow (Bos taurus) [TaxId: 9913]}
gpkfprvknwelgsitydtlcaqsqqdgpctprrclgslvlprklqtrpspgpppaeqll
sqardfinqyyssikrsgsqaheerlqeveaevastgtyhlreselvfgakqawrnaprc
vgriqwgklqvfdardcssaqemftyicnhikyatnrgnlrsaitvfpqrapgrgdfriw
nsqlvryagyrqqdgsvrgdpanveitelciqhgwtpgngrfdvlplllqapdeapelfv
lppelvlevplehptlewfaalglrwyalpavsnmlleigglefsaapfsgwymsteigt
rdlcdphryniledvavcmdldtrttsslwkdkaaveinlavlhsfqlakvtivdhhaat
vsfmkhldneqkarggcpadwawivppisgsltpvfhqemvnyilspafryqpdpw

Sequence, based on observed residues (ATOM records):

>d3n6ga_ d.174.1.1 (A:) Nitric oxide (NO) synthase oxygenase domain {Cow (Bos taurus) [TaxId: 9913]}
gpkfprvknwelgsitydtlcaqsqqdgpctprrclgslvlprpaeqllsqardfinqyy
ssikrsgsqaheerlqeveaevastgtyhlreselvfgakqawrnaprcvgriqwgklqv
fdardcssaqemftyicnhikyatnrgnlrsaitvfpqrapgrgdfriwnsqlvryagyr
qqdgsvrgdpanveitelciqhgwtpgngrfdvlplllqapdeapelfvlppelvlevpl
ehptlewfaalglrwyalpavsnmlleigglefsaapfsgwymsteigtrdlcdphryni
ledvavcmdldtrttsslwkdkaaveinlavlhsfqlakvtivdhhaatvsfmkhldneq
karggcpadwawivppisgsltpvfhqemvnyilspafryqpdpw

Timeline for d3n6ga_:

• d3n6ga_ first appeared in SCOPe 2.03
  
• d3n6ga_ appears in SCOPe 2.04
  
• d3n6ga_ appears in SCOPe 2.06
  
• d3n6ga_ appears in the current release, SCOPe 2.08