Lineage for d1sm3h2 (1sm3 H:114-213)

  1. Root: SCOP 1.73
  2. 651986Class b: All beta proteins [48724] (165 folds)
  3. 651987Fold b.1: Immunoglobulin-like beta-sandwich [48725] (27 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 651988Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 654118Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)
  6. 655111Protein Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574] (5 species)
  7. 655348Species Mouse (Mus musculus) [TaxId:10090] [88576] (330 PDB entries)
  8. 655449Domain d1sm3h2: 1sm3 H:114-213 [21361]
    Other proteins in same PDB: d1sm3h1, d1sm3l1, d1sm3l2
    part of tumor-specific Fab SM3 against epithelial mucin Muc1
    complexed with cd, cl

Details for d1sm3h2

PDB Entry: 1sm3 (more details), 1.95 Å

PDB Description: crystal structure of the tumor specific antibody sm3 complex with its peptide epitope
PDB Compounds: (H:) sm3 antibody

SCOP Domain Sequences for d1sm3h2:

Sequence, based on SEQRES records: (download)

>d1sm3h2 b.1.1.2 (H:114-213) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Mouse (Mus musculus) [TaxId: 10090]}
akttpptvyplapgsnaasqsmvtlgclvkgyfpepvtvtwnsgslasgvhtfpavlqsd
lytlsssvtvpsstwpsetvtcnvahpasstkvdakivpr

Sequence, based on observed residues (ATOM records): (download)

>d1sm3h2 b.1.1.2 (H:114-213) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Mouse (Mus musculus) [TaxId: 10090]}
akttpptvyplapgsmvtlgclvkgyfpepvtvtwnsgslasgvhtfpavlqsdlytlss
svtvpsstwpsetvtcnvahpasstkvdakivpr

SCOP Domain Coordinates for d1sm3h2:

Click to download the PDB-style file with coordinates for d1sm3h2.
(The format of our PDB-style files is described here.)

Timeline for d1sm3h2:

View in 3D
Domains from same chain:
(mouse over for more information)
d1sm3h1