SCOPe 2.08: Domain d3mo5c_: 3mo5 C:

Lineage for d3mo5c_ (3mo5 C:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.85: beta-clip [51268] (7 superfamilies)
   double-stranded ribbon sharply bent in two places; the ribbon ends form incomplete barrel; jelly-roll

4. Superfamily b.85.7: SET domain [82199] (4 families)
   duplication: the core is composed of two structural repeats similar to (circularly permuted) repeats of AFPIII
   also contains a substrate-binding alpha+beta subdomain inserted in the core
   Pfam PF00856

5. Family b.85.7.0: automated matches [227191] (1 protein)
   not a true family

6. Protein automated matches [226914] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [225158] (28 PDB entries)

8. Domain d3mo5c_: 3mo5 C: [213499]
   automated match to d1pega_
   complexed with e72, sah, zn

Details for d3mo5c_

PDB Entry: 3mo5, 2.14 Å

PDB Description: Human G9a-like (GLP, also known as EHMT1) in complex with inhibitor E72

PDB Compounds: (C:) Histone-lysine N-methyltransferase, H3 lysine-9 specific 5

SCOPe Domain Sequences for d3mo5c_:

Sequence, based on SEQRES records:

>d3mo5c_ b.85.7.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
verivsrdiargyeripipcvnavdsepcpsnykyvsqncvtspmnidrnithlqycvci
ddcsssncmcgqlsmrcwydkdgrllpefnmaepplifecnhacscwrncrnrvvqnglr
arlqlyrtrdmgwgvrslqdippgtfvceyvgelisdseadvreedsylfdldnkdgevy
cidarfygnvsrfinhhcepnlvpvrvfmahqdlrfpriaffstrlieageqlgfdyger
fwdikgklfscrcgspkcrhs

Sequence, based on observed residues (ATOM records):

>d3mo5c_ b.85.7.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
verivsrdiargyeripipcvnavdsepcpsnykyvsqncvtspmnidrnithlqycvci
ddcsssncmcgqlsmrcwydkdgrllpefnmaepplifecnhacscwrncrnrvvqnglr
arlqlyrtrdmgwgvrslqdippgtfvceyvgelisdseadvreedsylfdldgevycid
arfygnvsrfinhhcepnlvpvrvfmahqdlrfpriaffstrlieageqlgfdygerfwd
ikgklfscrcgspkcrhs

Timeline for d3mo5c_:

• d3mo5c_ first appeared in SCOPe 2.03
  
• d3mo5c_ appears in SCOPe 2.07