SCOPe 2.03: Domain d3mi9a_: 3mi9 A:

Lineage for d3mi9a_ (3mi9 A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Cell division protein kinase 9, CDK9 [160810] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [160811] (4 PDB entries)
   Uniprot P50750 8-325

8. Domain d3mi9a_: 3mi9 A: [213262]
   Other proteins in same PDB: d3mi9b1, d3mi9b2
   automated match to d3my1a_
   complexed with zn

Details for d3mi9a_

PDB Entry: 3mi9, 2.1 Å

PDB Description: Crystal structure of HIV-1 Tat complexed with human P-TEFb

PDB Compounds: (A:) Cell division protein kinase 9

SCOPe Domain Sequences for d3mi9a_:

Sequence, based on SEQRES records:

>d3mi9a_ d.144.1.7 (A:) Cell division protein kinase 9, CDK9 {Human (Homo sapiens) [TaxId: 9606]}
vecpfcdevskyeklakigqgtfgevfkarhrktgqkvalkkvlmenekegfpitalrei
kilqllkhenvvnlieicrtkaspynrckgsiylvfdfcehdlagllsnvlvkftlseik
rvmqmllnglyyihrnkilhrdmkaanvlitrdgvlkladfglarafslaknsqpnrytn
rvvtlwyrppelllgerdygppidlwgagcimaemwtrspimqgnteqhqlalisqlcgs
itpevwpnvdnyelyeklelvkgqkrkvkdrlkayvrdpyaldlidkllvldpaqridsd
dalnhdffwsdpmpsdlkgmlsthltsmfeylapprr

Sequence, based on observed residues (ATOM records):

>d3mi9a_ d.144.1.7 (A:) Cell division protein kinase 9, CDK9 {Human (Homo sapiens) [TaxId: 9606]}
vecpfcdevskyeklakigqgtfgevfkarhrktgqkvalkkvlmenekegfpitalrei
kilqllkhenvvnlieicrtkgsiylvfdfcehdlagllsnvlvkftlseikrvmqmlln
glyyihrnkilhrdmkaanvlitrdgvlkladfglarafslaknsqpnrytnrvvtlwyr
ppelllgerdygppidlwgagcimaemwtrspimqgnteqhqlalisqlcgsitpevwpn
vdnyelyeklelvkgqkrkvkdrlkayvrdpyaldlidkllvldpaqridsddalnhdff
wsdpmpsdlkgmlsthltsmfeylapprr

Timeline for d3mi9a_:

• d3mi9a_ is new in SCOPe 2.03-stable
  
• d3mi9a_ appears in SCOPe 2.04
  
• d3mi9a_ appears in the current release, SCOPe 2.08