Lineage for d3mcvc_ (3mcv C:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2090218Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2090219Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2090553Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 protein domains)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 2090925Protein Dihydropteridin reductase (pteridine reductase) [51769] (7 species)
  7. 2090996Species Trypanosoma brucei [TaxId:5702] [226783] (13 PDB entries)
  8. 2091011Domain d3mcvc_: 3mcv C: [213208]
    automated match to d1p33a_
    complexed with act, mcv, nap

Details for d3mcvc_

PDB Entry: 3mcv (more details), 1.7 Å

PDB Description: Structure of PTR1 from Trypanosoma brucei in ternary complex with 2,4-diamino-5-[2-(2,5-dimethoxyphenyl)ethyl]thieno[2,3-d]-pyrimidine and NADP+
PDB Compounds: (C:) pteridine reductase

SCOPe Domain Sequences for d3mcvc_:

Sequence, based on SEQRES records: (download)

>d3mcvc_ c.2.1.2 (C:) Dihydropteridin reductase (pteridine reductase) {Trypanosoma brucei [TaxId: 5702]}

Sequence, based on observed residues (ATOM records): (download)

>d3mcvc_ c.2.1.2 (C:) Dihydropteridin reductase (pteridine reductase) {Trypanosoma brucei [TaxId: 5702]}

SCOPe Domain Coordinates for d3mcvc_:

Click to download the PDB-style file with coordinates for d3mcvc_.
(The format of our PDB-style files is described here.)

Timeline for d3mcvc_: