![]() | Class b: All beta proteins [48724] (174 folds) |
![]() | Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies) sandwich; 7 strands in 2 sheets; greek-key some members of the fold have additional strands |
![]() | Superfamily b.1.1: Immunoglobulin [48726] (4 families) ![]() |
![]() | Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins) |
![]() | Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (5 species) |
![]() | Species Human (Homo sapiens) [TaxId:9606] [88569] (132 PDB entries) SQ NA # humanized antibody Uniprot P01834 # KAC_HUMAN Ig kappa chain C region SQ P01834 # KAC_HUMAN Ig kappa chain C region. SQ NA # engineered antibody including humanized antibodies (chimeric proteins with human constant domains) SQ NA # humanized antibody ! Uniprot P01834 # KAC_HUMAN Ig kappa chain C region ! SQ P01834 # KAC_HUMAN Ig kappa chain C region. ! SQ NA # engineered antibody |
![]() | Domain d1cz8x2: 1cz8 X:108-213 [21320] Other proteins in same PDB: d1cz8h1, d1cz8h2, d1cz8l1, d1cz8v_, d1cz8w_, d1cz8x1, d1cz8y1, d1cz8y2 part of humanized Fab-12 neutralizing VEGF; affinity matured complexed with so4; mutant |
PDB Entry: 1cz8 (more details), 2.4 Å
SCOP Domain Sequences for d1cz8x2:
Sequence; same for both SEQRES and ATOM records: (download)
>d1cz8x2 b.1.1.2 (X:108-213) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens) [TaxId: 9606]} rtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqd skdstyslsstltlskadyekhkvyacevthqglsspvtksfnrge
Timeline for d1cz8x2: