Lineage for d1ce1h2 (1ce1 H:122-220)

  1. Root: SCOP 1.73
  2. 651986Class b: All beta proteins [48724] (165 folds)
  3. 651987Fold b.1: Immunoglobulin-like beta-sandwich [48725] (27 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 651988Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 654118Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)
  6. 655111Protein Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574] (5 species)
  7. 655115Species Human (Homo sapiens) [TaxId:9606] [88575] (150 PDB entries)
    including humanized antibodies (chimeric proteins with human constant domains)
  8. 655148Domain d1ce1h2: 1ce1 H:122-220 [21311]
    Other proteins in same PDB: d1ce1h1, d1ce1l1, d1ce1l2
    part of humanized therapeutic antibody CAMPATH-1H

Details for d1ce1h2

PDB Entry: 1ce1 (more details), 1.9 Å

PDB Description: 1.9a structure of the therapeutic antibody campath-1h fab in complex with a synthetic peptide antigen
PDB Compounds: (H:) protein (campath-1h:heavy chain)

SCOP Domain Sequences for d1ce1h2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1ce1h2 b.1.1.2 (H:122-220) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Human (Homo sapiens) [TaxId: 9606]}
astkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkkve

SCOP Domain Coordinates for d1ce1h2:

Click to download the PDB-style file with coordinates for d1ce1h2.
(The format of our PDB-style files is described here.)

Timeline for d1ce1h2:

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Domains from same chain:
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d1ce1h1