Lineage for d3ly2b_ (3ly2 B:)

  1. Root: SCOPe 2.05
  2. 1715731Class a: All alpha proteins [46456] (286 folds)
  3. 1753307Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
    multihelical; consists of two different alpha-helical bundles
  4. 1753308Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families) (S)
  5. 1753393Family a.211.1.2: PDEase [48548] (7 protein domains)
    Pfam PF00233; multihelical; can be divided into three subdomains
  6. 1753397Protein Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b [48549] (1 species)
  7. 1753398Species Human (Homo sapiens) [TaxId:9606] [48550] (28 PDB entries)
    Uniprot Q07343 324-667
  8. 1753436Domain d3ly2b_: 3ly2 B: [213096]
    automated match to d3d3pa_
    complexed with mg, so4, z72, zn

Details for d3ly2b_

PDB Entry: 3ly2 (more details), 2.6 Å

PDB Description: Catalytic Domain of Human Phosphodiesterase 4B in Complex with A Coumarin-Based Inhibitor
PDB Compounds: (B:) cAMP-specific 3',5'-cyclic phosphodiesterase 4B

SCOPe Domain Sequences for d3ly2b_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3ly2b_ a.211.1.2 (B:) Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d3ly2b_:

Click to download the PDB-style file with coordinates for d3ly2b_.
(The format of our PDB-style files is described here.)

Timeline for d3ly2b_: