Lineage for d3lxpa_ (3lxp A:)

  1. Root: SCOPe 2.07
  2. 2530962Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2586062Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2586063Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2591262Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2591263Protein automated matches [190417] (35 species)
    not a true protein
  7. 2591422Species Human (Homo sapiens) [TaxId:9606] [187294] (1319 PDB entries)
  8. 2591459Domain d3lxpa_: 3lxp A: [213094]
    automated match to d3lpbb_
    complexed with iza

Details for d3lxpa_

PDB Entry: 3lxp (more details), 1.65 Å

PDB Description: structural and thermodynamic characterization of the tyk2 and jak3 kinase domains in complex with cp-690550 and cmp-6
PDB Compounds: (A:) Non-receptor tyrosine-protein kinase TYK2

SCOPe Domain Sequences for d3lxpa_:

Sequence, based on SEQRES records: (download)

>d3lxpa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dptvfhkrylkkirdlgeghfgkvslycydptndgtgemvavkalkadagpqhrsgwkqe
idilrtlyhehiikykgccedagaaslqlvmeyvplgslrdylprhsiglaqlllfaqqi
cegmaylhaqhyihrdlaarnvlldndrlvkigdfglakavpegheyyrvredgdspvfw
yapeclkeykfyyasdvwsfgvtlyellthcdssqspptkfleligiaqgqmtvlrltel
lergerlprpdkcpaevyhlmkncweteasfrptfenlipilktvhekyqg

Sequence, based on observed residues (ATOM records): (download)

>d3lxpa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dptvfhkrylkkirdlgeghfgkvslycydptntgemvavkalkadagpqhrsgwkqeid
ilrtlyhehiikykgccedagaaslqlvmeyvplgslrdylprhsiglaqlllfaqqice
gmaylhaqhyihrdlaarnvlldndrlvkigdfglakavpegheyyrvgdspvfwyapec
lkeykfyyasdvwsfgvtlyellthcdssqspptkfleligiaqgqmtvlrltellerge
rlprpdkcpaevyhlmkncweteasfrptfenlipilktvhekyqg

SCOPe Domain Coordinates for d3lxpa_:

Click to download the PDB-style file with coordinates for d3lxpa_.
(The format of our PDB-style files is described here.)

Timeline for d3lxpa_: