SCOPe 2.07: Domain d3loka_: 3lok A:

Lineage for d3loka_ (3lok A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (35 species)
   not a true protein

7. Species Chicken (Gallus gallus) [TaxId:9031] [225619] (9 PDB entries)

8. Domain d3loka_: 3lok A: [212981]
   automated match to d2gqgb_
   complexed with djk

Details for d3loka_

PDB Entry: 3lok, 2.48 Å

PDB Description: Drug resistant cSrc kinase domain in complex with covalent inhibitor PD168393

PDB Compounds: (A:) Proto-oncogene tyrosine-protein kinase Src

SCOPe Domain Sequences for d3loka_:

Sequence, based on SEQRES records:

>d3loka_ d.144.1.0 (A:) automated matches {Chicken (Gallus gallus) [TaxId: 9031]}
kdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqeaqvmkk
lrheklvqlyavvseepiyivmeymskgclldflkgemgkylrlpqlvdmaaqiasgmay
vermnyvhrdlraanilvgenlvckvadfglarliedneytarqgakfpikwtapeaaly
grftiksdvwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmc
qcwrkdpeerptfeylqafledyftstepqyqpgenl

Sequence, based on observed residues (ATOM records):

>d3loka_ d.144.1.0 (A:) automated matches {Chicken (Gallus gallus) [TaxId: 9031]}
kdaweipreslrlevklgfgevwmgtwngttrvaiktleaqvmkklrheklvqlyavvse
epiyivmeymskgclldflkgemgkylrlpqlvdmaaqiasgmayvermnyvhrdlraan
ilvgenlvckvadfglarlpikwtapeaalygrftiksdvwsfgilltelttkgrvpypg
mvnrevldqvergyrmpcppecpeslhdlmcqcwrkdpeerptfeylqafledyftstep
qyqpgenl

Timeline for d3loka_:

• d3loka_ first appeared in SCOPe 2.03
  
• d3loka_ appears in SCOPe 2.06
  
• d3loka_ appears in the current release, SCOPe 2.08