SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d3llpb2 (3llp B:141-259)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2053108Fold b.42: beta-Trefoil [50352] (8 superfamilies)
    barrel, closed; n=6, S=12; and a hairpin triplet; meander
    duplication: has internal pseudo threefold symmetry
  4. 2054015Superfamily b.42.5: Actin-crosslinking proteins [50405] (3 families) (S)
  5. 2054016Family b.42.5.1: Fascin [50406] (1 protein)
    automatically mapped to Pfam PF06268
  6. 2054017Protein Fascin [50407] (1 species)
    duplication: tandem repeat of four domains
  7. 2054018Species Human (Homo sapiens) [TaxId:9606] [50408] (8 PDB entries)
  8. 2054024Domain d3llpb2: 3llp B:141-259 [212931]
    automated match to d1dfca2
    complexed with br, epe, gol, k, so4

Details for d3llpb2

PDB Entry: 3llp (more details), 1.8 Å

PDB Description: 1.8 Angstrom human fascin 1 crystal structure
PDB Compounds: (B:) fascin

SCOPe Domain Sequences for d3llpb2:

Sequence, based on SEQRES records: (download)

>d3llpb2 b.42.5.1 (B:141-259) Fascin {Human (Homo sapiens) [TaxId: 9606]}
qvniysvtrkryahlsarpadeiavdrdvpwgvdslitlafqdqrysvqtadhrflrhdg
rlvarpepatgytlefrsgkvafrdcegrylapsgpsgtlkagkatkvgkdelfaleqs

Sequence, based on observed residues (ATOM records): (download)

>d3llpb2 b.42.5.1 (B:141-259) Fascin {Human (Homo sapiens) [TaxId: 9606]}
qvniysvtrkryahlsaadeiavdrdvpwgvdslitlafqdqrysvqtadhrflrhdgrl
varpepatgytlefrsgkvafrdcegrylapsgpsgtlkagkatkvgkdelfaleqs

SCOPe Domain Coordinates for d3llpb2:

Click to download the PDB-style file with coordinates for d3llpb2.
(The format of our PDB-style files is described here.)

Timeline for d3llpb2: