Lineage for d1a4jh2 (1a4j H:120-217)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2020524Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 protein domains)
  6. 2022294Protein Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574] (6 species)
  7. 2022298Species Human (Homo sapiens) [TaxId:9606] [88575] (179 PDB entries)
    including humanized antibodies (chimeric proteins with human constant domains)
    Uniprot Q6N089 20-243 # 95% sequence identity; natural chimera: antibody heavy chain (Fab HYB3) ! SQ NA # humanized antibody ! Uniprot P01857 # IGHG1_HUMAN Ig gamma-1 chain C region ! SQ NA # engineered antibody
  8. 2022405Domain d1a4jh2: 1a4j H:120-217 [21243]
    Other proteins in same PDB: d1a4ja1, d1a4ja2, d1a4jb1, d1a4jh1, d1a4jl1, d1a4jl2
    part of humanized Diels-Alder catalytic Fab

Details for d1a4jh2

PDB Entry: 1a4j (more details), 2.1 Å

PDB Description: diels alder catalytic antibody germline precursor
PDB Compounds: (H:) immunoglobulin, diels alder catalytic antibody (heavy chain)

SCOPe Domain Sequences for d1a4jh2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1a4jh2 b.1.1.2 (H:120-217) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1a4jh2:

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Timeline for d1a4jh2: