SCOPe 2.08: Domain d3km6a1: 3km6 A:2-78

Lineage for d3km6a1 (3km6 A:2-78)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.47: Thioredoxin fold [52832] (2 superfamilies)
   core: 3 layers, a/b/a; mixed beta-sheet of 4 strands, order 4312; strand 3 is antiparallel to the rest

4. Superfamily c.47.1: Thioredoxin-like [52833] (24 families)

5. Family c.47.1.0: automated matches [191312] (1 protein)
   not a true family

6. Protein automated matches [190056] (195 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188013] (113 PDB entries)

8. Domain d3km6a1: 3km6 A:2-78 [212419]
   Other proteins in same PDB: d3km6a2, d3km6b2
   automated match to d1gssa2
   complexed with ca, eaa, gsh; mutant

Details for d3km6a1

PDB Entry: 3km6, 2.1 Å

PDB Description: crystal structure of the human gst pi c47s/y108v double mutant in complex with the ethacrynic acid-glutathione conjugate

PDB Compounds: (A:) Glutathione S-transferase P

SCOPe Domain Sequences for d3km6a1:

Sequence; same for both SEQRES and ATOM records:

>d3km6a1 c.47.1.0 (A:2-78) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pytvvyfpvrgrcaalrmlladqgqswkeevvtvetwqegslkasslygqlpkfqdgdlt
lyqsntilrhlgrtlgl

Timeline for d3km6a1:

• d3km6a1 first appeared in SCOPe 2.03
  
• d3km6a1 appears in SCOPe 2.07