Lineage for d3kc3e_ (3kc3 E:)

  1. Root: SCOPe 2.07
  2. 2530962Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2586062Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2586063Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2586210Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2588367Protein MAP kinase activated protein kinase 2, mapkap2 [82789] (1 species)
    CaMK group; MAPKAPK subfamily; serine/threonine kinase
  7. 2588368Species Human (Homo sapiens) [TaxId:9606] [82790] (16 PDB entries)
  8. 2588404Domain d3kc3e_: 3kc3 E: [212277]
    automated match to d1nxkc_
    complexed with mk2

Details for d3kc3e_

PDB Entry: 3kc3 (more details), 2.9 Å

PDB Description: MK2 complexed to inhibitor N4-(7-(benzofuran-2-yl)-1H-indazol-5-yl)pyrimidine-2,4-diamine
PDB Compounds: (E:) MAP kinase-activated protein kinase 2

SCOPe Domain Sequences for d3kc3e_:

Sequence, based on SEQRES records: (download)

>d3kc3e_ d.144.1.7 (E:) MAP kinase activated protein kinase 2, mapkap2 {Human (Homo sapiens) [TaxId: 9606]}
pqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkarr
evelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgdqafterea
seimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettshnslttp
cytpyyvapevlgpekydkscdmwslgvimyillcgyppfysnhglaispgmktrirmgq
yefpnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstkvpqtplhtsrvlk
ed

Sequence, based on observed residues (ATOM records): (download)

>d3kc3e_ d.144.1.7 (E:) MAP kinase activated protein kinase 2, mapkap2 {Human (Homo sapiens) [TaxId: 9606]}
pqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkarr
evelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgdqafterea
seimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettpyyvapev
lgpekydkscdmwslgvimyillcgyppfysnispgmktrirmgqyefpnpewsevseev
kmlirnllkteptqrmtitefmnhpwimqstkvpqtplhtsrvlked

SCOPe Domain Coordinates for d3kc3e_:

Click to download the PDB-style file with coordinates for d3kc3e_.
(The format of our PDB-style files is described here.)

Timeline for d3kc3e_: