Lineage for d1ad9b2 (1ad9 B:114-212)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2739517Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2739518Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2745637Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)
  6. 2747669Protein Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574] (7 species)
  7. 2747676Species Human (Homo sapiens) [TaxId:9606] [88575] (173 PDB entries)
    including humanized antibodies (chimeric proteins with human constant domains)
    Uniprot Q6N089 20-243 # 95% sequence identity; natural chimera: antibody heavy chain (Fab HYB3) ! SQ NA # humanized antibody ! Uniprot P01857 # IGHG1_HUMAN Ig gamma-1 chain C region ! SQ NA # engineered antibody
  8. 2747834Domain d1ad9b2: 1ad9 B:114-212 [21227]
    Other proteins in same PDB: d1ad9a1, d1ad9a2, d1ad9b1, d1ad9h1, d1ad9l1, d1ad9l2
    part of humanized Fab CTM01
    complexed with so4

Details for d1ad9b2

PDB Entry: 1ad9 (more details), 2.8 Å

PDB Description: igg-fab fragment of engineered human monoclonal antibody ctm01
PDB Compounds: (B:) igg ctm01 fab (heavy chain)

SCOPe Domain Sequences for d1ad9b2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1ad9b2 b.1.1.2 (B:114-212) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Human (Homo sapiens) [TaxId: 9606]}
astkgpsvfplapcsrstsestaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtktytcnvdhkpsntkvdkrve

SCOPe Domain Coordinates for d1ad9b2:

Click to download the PDB-style file with coordinates for d1ad9b2.
(The format of our PDB-style files is described here.)

Timeline for d1ad9b2: